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1

Factor VII deficiency and the FVII mutation database

John H. McVey, Emma Boswell, Andrew D. Mumford, Geoffrey Kemball-Cook, Edward G.D. Tuddenham

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 476 KB

english, 2001

2

Stable recombinant expression and characterization of the two haemophilic factor VIII variants C329S (CRM−) and G1948D (CRMr)

Dezsö David, Evgueni L. Saenko, I. M. Ana Santos, Daniel J. D. Johnson, Edward G. D. Tuddenham, John H. McVey, Geoffrey Kemball-Cook

Journal:

British Journal of Haematology

Année:

2001

Langue:

english

Fichier:

PDF, 182 KB

english, 2001

3

A Tyr346→Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII:C assay discrepancy

Andrew D. Mumford, Michael Laffan, James O'Donnell, John H. McVey, Daniel J. D. Johnson, Richard A. Manning, Geoffrey Kemball-Cook

Journal:

British Journal of Haematology

Année:

2002

Langue:

english

Fichier:

PDF, 180 KB

english, 2002

4

Use of a non-depleting anti-CD4 antibody to modulate the immune response to coagulation factors VIII and IX

Nina Salooja, Geoffrey Kemball-Cook, Edward G. D. Tuddenham, Julian Dyson

Journal:

British Journal of Haematology

Année:

2002

Langue:

english

Fichier:

PDF, 210 KB

english, 2002

5

Factor VIII – novel insights into form and function

Evgueni L. Saenko, Natalya M. Ananyeva, Edward G. D. Tuddenham, Geoffrey Kemball-Cook

Journal:

British Journal of Haematology

Année:

2002

Langue:

english

Fichier:

PDF, 414 KB

english, 2002

6

Two novel mutations in severe factor VII deficiency

Keith Gomez, Michael A. Laffan, Geoffrey Kemball-Cook, John Pasi, Mark Layton, Jack D. Singer, Edward G. D. Tuddenham, John H. McVey

Journal:

British Journal of Haematology

Année:

2004

Langue:

english

Fichier:

PDF, 455 KB

english, 2004

7

A novel role for the Aurora B kinase in epigenetic marking of silent chromatin in differentiated postmitotic cells

Sabbattini, Pierangela, Canzonetta, Claudia, Sjoberg, Marcela, Nikic, Svetlana, Georgiou, Andrew, Kemball-Cook, Geoffrey, Auner, Holger W, Dillon, Niall

Journal:

The EMBO Journal

Année:

2007

Langue:

english

Fichier:

PDF, 630 KB

english, 2007

8

Two-dimensional crystallisation of blood coagulation factor VIIa and the factor VIIa/antitrombine III complex

Rebecka Bold, Svetla Stoylova, Andreas Holzenburg, Geoffrey Kemball-Cook

Journal:

Biology of the Cell

Année:

1998

Langue:

english

Fichier:

PDF, 162 KB

english, 1998

9

Variable inactivation of human factor VIII from different sources by human factor VIII inhibitors

Janet D. Littlewood, Sally A. Bevan, Geoffrey Kemball-Cook, Richard J. Evans, Trevor W. Barrowcliffe

Journal:

British Journal of Haematology

Année:

1991

Langue:

english

Fichier:

PDF, 372 KB

english, 1991

10

Complete Inhibition of Acute Humoral Rejection Using Regulated Expression of Membrane-tethered Anticoagulants on Xenograft Endothelium

Daxin Chen, Michele Weber, John H. McVey, Geoffrey Kemball-Cook, Edward G. D. Tuddenham, Robert I. Lechler, Anthony Dorling

Journal:

American Journal of Transplantation

Année:

2004

Langue:

english

Fichier:

PDF, 206 KB

english, 2004

11

Crystallization and Preliminary X-Ray Analysis of Active Site-Inhibited Human Coagulation Factor VIIa (des-Gla)

Daniel J.D. Johnson, Philip G. Nugent, Edward G.D. Tuddenham, Karl Harlos, Geoffrey Kemball-Cook

Journal:

Journal of Structural Biology

Année:

1999

Langue:

english

Fichier:

PDF, 150 KB

english, 1999

12

Crystal Structure of Active Site-Inhibited Human Coagulation Factor VIIa (des-Gla)

Geoffrey Kemball-Cook, Daniel J.D. Johnson, Edward G.D. Tuddenham, Karl Harlos

Journal:

Journal of Structural Biology

Année:

1999

Langue:

english

Fichier:

PDF, 417 KB

english, 1999

13

Factor VIIa and the extracellular domains of human tissue factor form a compact complex: A study by X-ray and neutron solution scattering

Alun W. Ashton, Geoffrey Kemball-Cook, Daniel J.D. Johnson, David M.A. Martin, Donogh P. O'Brien, Edward G.D. Tuddenham, Stephen J. Perkins

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 581 KB

english, 1995

14

In silico prediction of FVIII epitopes recognised by natural autoantibodies in polyvalent immunoglobulin concentrates

Mario Di Giambattista, Theo Branckaert, Vincent Hougardy, Geoffrey Kemball-Cook, Ruth Laub

Journal:

Molecular Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

15

Interaction of factor VIII with phospholipids: Role of composition and negative charge

Geoffrey Kemball-Cook, Trevor W Barrowcliffe

Journal:

Thrombosis Research

Année:

1992

Langue:

english

Fichier:

PDF, 1.04 MB

english, 1992

16

High-level production of human blood coagulation factors VII and XI using a new mammalian expression vector

Kemball-Cook, Geoffrey, Garner, Ian, Imanaka, Yasufumi, Nishimura, Takuya, O'Brien, Donogh P., Tuddenham, Edward G.D., McVey, John H.

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 512 KB

english, 1994

17

Potency of high purity factor VIII concentrates

Barrowcliffe, TrevorW., Watton, Jane, Harman, Andrew, Tubbs, JillE., Kemball-Cook, Geoffrey

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 170 KB

english, 1990

18

Detection of missense mutations by single-strand conformational polymorphism (SSCP) analysis in five dysfunctional variants of coagulation factor VII

Takamlya, Osamu, Kemball-Cook, Geoffrey, Martin, David M.A., Cooper, David N., von Felten, Arthur, Melll, Esther, Hann, Ian, Prangnell, Dennls R., Lumley, Hllary, Tuddenham, Edward G.D., McVey, John H

Journal:

Human Molecular Genetics

Année:

1993

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1993

19

EXPRESSION OF NOVEL ANTICOAGULANT FUSION PROTEINS INHIBITS FACTOR XA- AND THROMBIN-INDUCED ACTIVATION OF PORCINE VASCULAR ENDOTHELIAL CELLS.

Daxin, Chen, Riesbeck, Kristian, McVey, John, Kemball-Cook, Geoffrey, Tuddenham, Edward G.D., Lechler, Robert I., Dorling, Anthony

Journal:

Transplantation Journal

Année:

2000

Fichier:

PDF, 943 KB

2000

20

Two Novel Mutations in Severe Factor VII Deficiency

Gomez, Keith, Laffan, Michael A., Kemball-Cook, Geoffrey, Pasi, John, Layton, Mark, Tuddenham, Edward G.D., McVey, John

Journal:

Clinical Science

Année:

2003

Langue:

english

Fichier:

PDF, 125 KB

english, 2003

21

Characterisation of blood coagulation factor XIT475I

McVey, John, Lal, Kalpana, Imanaka, Yasufumi, Kemball-Cook, Geoffrey, Bolton-Maggs, Paula, Tuddenham, Edward

Journal:

Thrombosis and Haemostasis

Année:

2005

Langue:

english

Fichier:

PDF, 533 KB

english, 2005

22

Hemophilia A Mutations within the Factor VIII A2-A3 Subunit Interface Destabilize Factor VIIIa and Cause One-stage/ Two-stage Activity Discrepancy

Hakeos, William, Miao, Hongzhi, Sirachainan, Nongnuch, Kemball-Cook, Geoffrey, Saenko, Evgueni, Kaufman, Randal, Pipe, Steven

Journal:

Thrombosis and Haemostasis

Année:

2002

Langue:

english

Fichier:

PDF, 216 KB

english, 2002

23

The Molecular Basis for Cross-Reacting MaterialâPositive Hemophilia A Due to Missense Mutations Within the A2-Domain of Factor VIII

Amano, Kagehiro, Sarkar, Rita, Pemberton, Susan, Kemball-Cook, Geoffrey, Kazazian, Haig H., Kaufman, Randal J.

Journal:

Année:

1998

Fichier:

PDF, 637 KB

1998